The sequel to the 1998 Eddie Murphy vehicle sees Dolittle (Murphy) having to save an endangered species, the Pacific Western Bear, and its natural habitat, a forest that is under threat from the lumber industry. The trouble is he only has three weeks to find a mate for the lone female of the species (voiced by Lisa Kudrow) left in the wild and the only candidate he can come up with is a performing bear (voiced by Steve Zahn) with a penchant for junk food. Not only has Dolittle got a massive task on his hands he also has to contend with the forest's animal version of the Mafia.