A heroine for the modern age, district nurse Frankie Maddox looks life and death in the eye on a daily basis; her mission is to make a difference.

Heart warming and funny Frankie follows the eclectic team as they visit their patients at home and takes a look at ordinary lives, which are often in huge domestic crises.

The nurses enjoy their work; it may infuriate, frustrate and even bore them at times, but they turn up day in and day out and wouldn't choose to do anything else - even when missed birthday parties and emotionally neglected kids are the order of the day. All that matters, whatever their flaws, is that they do a good day's work, and make life better for their patients.