Debuting as the top seller for its launch in Japan, Shin Megami Tensei IV: Apocalypse (SMT4A)depicts the remnants of Tokyo ravaged by a catastrophe. Demons and humans co-exist, but in this state the remains of humankind are just a prize being fought over by the higher deities.

One lone Hunter, the game's protagonist, meets an early demise and through a pact with a lesser god is brought back to life in exchange for his pledge of servitude. From there, the protagonist allies with other Hunters in the ruins of post-apocalyptic Tokyo, beginning a plot that crosses over with the events of the original Shin Megami Tensei IV.